|
KMID : 1189320160100061149
|
|
Asian Spine Journal
2016 Volume.10 No. 6 p.1149 ~ p.1156
|
|
|
Bone Union Rate Following Instrumented Posterolateral Lumbar Fusion: Comparison between Demineralized Bone Matrix versus Hydroxyapatite
|
|
Nam Woo-Dong
Yi Je-Min
|
|
|
Abstract
|
|
|
Study Design: Retrospective study.
Purpose: To compare the union rate of posterolateral lumbar fusion (PLF) using demineralized bone matrix (DBM) versus hydroxyapatite (HA) as bone graft extender.
Overview of Literature: To our knowledge, there has been no clinical trial to compare the outcomes of DBM versus HA as a graft material for PLF.
Methods: We analyzed prospectively collected data from consecutive 79 patients who underwent instrumented PLF. Patients who received DBM were assigned to group B (n=38), and patients who received HA were assigned into group C (n=41). The primary study outcome was fusion rate assessed with radiographs. The secondary outcomes included pain intensity using a visual analogue scale, functional outcome using Oswestry disability index score, laboratory tests of inflammatory profiles and infection rate.
Results: One year postoperatively, bone fusion was achieved in 73% in group B and 58% in group C without significant difference between the groups (p=0.15). There were no differences between the groups with respect to secondary outcomes.
Conclusions: DBM would provide noninferior outcomes compared to the HA as a fusion material for PLF, and could be a notable alternative.
|
|
|
KEYWORD
|
|
|
Posterolateral lumbar fusion, Demineralized bone matrix, Hydroxyapatites
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|